This paper deals with the adaptive control of fractional-order micro-electro-mechanical resonator system (FOMEMRS) with nonsymmetric dead-zone nonlinear input. The slope parameters of the dead-zone nonlinearity are unmeasured and the parameters of the controlled systems are assumed to be unknown in advance. To deal with these unknown parameters, some fractional versions of parametric update laws are proposed. On the basis of the frequency distributed model of fractional integrator and Lyapunov stability theory, a robust control law is designed to prove the stability of the closed-loop system. The proposed adaptive approach requires only the information of bounds of the dead-zone slopes and treats the time-varying input coefficient as a system uncertainty. Finally, simulation examples are given to verify the robustness and effectiveness of the proposed control scheme.