This paper investigates the control and synchronization of a class of chaotic systems with external disturbance. The chaotic systems are assumed that only the output state variable is available. By using the output state variable, two types synchronization schemes, i.e., the chaos-based synchronization and the observer-based synchronization schemes, are discussed. Some novel criteria for the control and synchronization of a class of chaotic systems with external disturbance are proposed. The unified chaotic system is taken as an example to demonstrate the efficiency of the proposed approach.