Abstract

We have demonstrated a non-contact method of concentrating and mixing particles in a plastic microfluidic chamber employing acoustic radiation pressure. A flow cell package has also been designed that integrates liquid sample interconnects, electrical contacts and a removable sample chamber. Increased antibody binding to magnetic porous glass beads was observed in the presence of acoustic mixing due to improved mass transport. Concentration of glass and polystyrene beads using acoustic radiation pressure was also demonstrated.

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