This article presents a numerical investigation carried out to determine the effects of second and third injection timing on combustion characteristics and mixture formation of a gasoline direct injection (GDI) engine by comparing conical spray against multihole spray. The results showed that at the engine 80% full load of 2000 r/min, the difference in mixture distribution between the two sprays was obvious with double and triple injection strategies. With the second injection timing from 140 deg CA delay to 170 deg CA, the in-cylinder pressure, the in-cylinder temperature, and the heat release rate of the conical spray increased by 20.8%, 9.8%, and 30.7% and that of the multihole spray decreased by 30.7%, 13.6%, and 37.8%. The delay of the injection time reduced the performance of the engine with the multihole spray, and the performance of the multihole spray was obviously in the simulation of the triple injection strategy. However, for the conical spray, the application of the triple injection strategy increased the temperature and the pressure compared with the double injection strategy.