This paper presents an optimal synthesis method for path generation of planar mechanisms, in which a new path-description method named refined numerical representation is proposed to define the object function of the optimization model for path generation, and then the artificial immune network searching method is introduced to search candidate solutions. As a result, desired mechanisms can be generated independent of the scale, rotation, and translation transformation as well as sampling uniformity of initial sampling points. Experiment results demonstrate the effectiveness of the approach.

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